VIP: Research Profile, Dosages & Supplier Prices
VIP is a neuropeptide research compound with a molecular weight of 3325.8 g/mol and a research half-life of ~1-2 minutes (plasma); longer inhaled. VIP (vasoactive intestinal peptide) is a 28-amino-acid neuropeptide of the secretin/glucagon family, originally isolated from intestine but now known to be widely distributed through the nervous, immune, cardiovascular and pulmonary systems. It is a potent vasodilator, bronchodilator and immunomodulator with an unusually broad physiological footprint.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 |
| Formula | C147H238N44O42S |
| Mol. weight | 3325.8 g/mol |
| Half-life | ~1-2 minutes (plasma); longer inhaled |
| Forms sold | Lyophilized powder |
What is VIP?
A synthetic form (aviptadil) has been investigated clinically for pulmonary hypertension, ARDS, sarcoidosis and critical COVID-19, typically by inhalation to exploit its short plasma half-life. In research, VIP is a key tool for studying VPAC1/VPAC2 receptor signaling, circadian rhythm regulation in the suprachiasmatic nucleus, and immune tolerance - it shifts immune responses toward anti-inflammatory Th2/Treg profiles. Its extreme plasma instability (half-life of about a minute) is the central experimental challenge.
Mechanism of Action (Research Context)
Agonist at VPAC1 and VPAC2 Gs-coupled receptors, raising cAMP. Produces vasodilation, bronchodilation, increased secretion, and immunomodulation (suppressed Th1 responses, induced regulatory T cells). Degraded rapidly by neutral endopeptidases.
Research Areas
VIP Dosages in Research
Clinical aviptadil research used inhaled or IV dosing in microgram ranges given the ~1-minute plasma half-life. Research-context only.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Lyophilized: -20C desiccated. Reconstituted: 2-8C and use quickly - among the least stable catalog peptides in solution; aliquot and freeze at -80C for longer storage.
VIP Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| Peptides, Steroid Powders & Biochemical Raw Materials | VIP Peptide (Vasoactive Intestinal Peptide) 5mg / 10mg Lyophilized Powder – Research Peptide Material 5mg / 10mg | — | ★ 1.8 |
| Wholesale high | VIP Peptide 5-10mg Raw material wholesale 5-10mg | $10.00 | ★ 2.6 |
| Bangkok Peptide Center | VIP 10mg 10mg | $20.00 | ★ 1.6 |
| Pure Peptides UK | VIP 10mg 10mg | $28.99 | ★ 2.7 |
| Research Peptides UK | Adonis VIP – Research Peptide (RUO) | $29.99 | ★ 2.0 |
| Home | VIP Peptides | $37.00 | ★ 1.8 |
| AIO Peptides: Buy High | VIP 5mg 5mg | $48.00 | ★ 2.0 |
| Home | VIP 5mg 5mg | $48.00 | ★ 2.9 |
| Advanced Peptide Research | VIP | $49.99 | ★ 1.9 |
| Research Peptides & Laboratory Materials | VIP 5mg | $52.00 | ★ 2.6 |
| Go Alpha Labs | VIP (5mg) 5mg | $52.99 | ★ 2.9 |
| Home | VIP | 10mg | Research Use Only 10mg | $54.99 | ★ 2.2 |
| Research Peptides in the USA | VIP (Vasoactive Intestinal Peptide) Peptide | $57.00 | ★ 2.1 |
| Home | VIP 10mg 10mg | $58.00 | ★ 2.5 |
| Ascension Peptides – Your premiere source for research peptides | VIP (10MG) 10mg | $58.00 | ★ 2.3 |
| Atomik Labs Peptides: Buy High | VIP – 7.5mg 7.5mg | $59.00 | ★ 2.3 |
| Just Compounds | VIP | $59.99 | ★ 1.7 |
| Home | VIP Peptide 5mg Online. 5mg | $60.00 | ★ 2.3 |
| Modern Aminos: USA's Trusted Store for Quality Research Chemicals | VIP (Vasoactive Intestinal Peptide) | $60.00 | ★ 3.0 |
| Home | Core Peptides VIP (6mg) 6mg | $64.00 | ★ 2.3 |
| Home | VIP | $65.00 | ★ 1.6 |
| Home | VIP 10mg 10mg | $68.00 | ★ 1.9 |
| 24Peptides | VIP (Vasoactive Intestinal Peptide) 10mg 10mg | $69.00 | ★ 2.2 |
| Buy Peptides for Scientific Research | VIP 5mg 5mg | $69.99 | ★ 2.2 |
| Peptides Canada | VIP (Vasoactive Intestinal Peptide) 5 mg 5mg | $69.99 | ★ 2.1 |
| Research Peptides — Third | VIP10 (10mg) 10mg | $70.99 | ★ 1.9 |
| Home | VIP 10mg 10mg | $74.00 | ★ 1.9 |
| Elitecare Pharmacy – Advanced Peptide Solutions. Precision You Can Trust. | VIP | $78.00 | ★ 1.8 |
| American Peptide Innovations | VIP10 (10mg) 10mg | $80.00 | ★ 1.9 |
| Ascension Peptides | VIP 10mg Research Peptide 10mg | $80.00 | ★ 1.7 |
| Home | VIP Peptide – 5mg-10mg Bulk supply 5mg-10mg | $81.00 | ★ 2.2 |
| RUO peptides — Amino Connection | VIP | $84.00 | ★ 1.7 |
| Aavant Research Peptide | VIP | $85.00 | ★ 2.3 |
| Azoth Peptides | VIP | $85.00 | ★ 1.7 |
| American Select Peptides – Research peptides and analytical standards for qualified laboratories. | VIP | $89.00 | ★ 1.7 |
| Meridian Compounds – Research Compounds | VIP | $95.00 | ★ 1.6 |
| Apex Gains LLC | VIP (Vasoactive Intestinal Peptide) | $100.00 | ★ 2.1 |
| 808 Peptides LLC | VIP10 (10mg) 10mg | $108.00 | ★ 1.9 |
| LUXE AMINOS | VIP 10mg 10mg | $119.00 | ★ 2.8 |
| Verified Wholesale Peptides | VIP (Vasoactive Intestinal Peptide) | 10mg x 10 Vials Kit | >99% Purity 10mg | $130.00 | ★ 2.0 |
| Home | VIP (10MG) 10MG | $149.00 | ★ 1.8 |
| Age Verification | VIP 10MG 10MG | $150.00 | ★ 1.8 |
| Nature's Evolution LLC | VIP | $154.00 | ★ 1.8 |
| Alpha Amino Labs | VIP10 (10mg) 10mg | $190.00 | ★ 1.9 |
| Home | VIP | $198.00 | ★ 1.8 |
| Buy Australia Research Peptides | VIP Peptide | $214.00 | ★ 1.9 |
| Ascend Peptides | VIP | $227.99 | ★ 1.9 |
| Home | VIP 10mg (10 vials/kit) 10mg | $285.00 | ★ 1.8 |
| Go Alpha Labs | VIP (5mg) (10 Vials) 5mg | $399.99 | ★ 2.9 |