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All products discussed on this site are Research Use Only (RUO) compounds intended strictly for laboratory research. Nothing here is medical advice, and these products are not for human or veterinary use.

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TB-500: Research Profile, Dosages & Supplier Prices

Repair / recovery research · Lyophilized vial · Also known as: Thymosin Beta-4 fragment, TB4, TB-500 fragment

TB-500 is a repair / recovery research compound with a molecular weight of ~889 g/mol (fragment) and a research half-life of longer-acting than parent thymosin beta-4 in preclinical models due to fragment design. TB-500 is a synthetic research peptide based on the active region of Thymosin Beta-4, a naturally occurring 43-amino-acid protein involved in actin regulation and cell migration. The fragment design was developed to retain the regions most studied for tissue repair while improving stability and synthesis economics.

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

SequenceSynthetic fragment based on the active region of Thymosin Beta-4
FormulaC38H68N10O14 (fragment region)
Mol. weight~889 g/mol (fragment)
Half-lifeLonger-acting than parent thymosin beta-4 in preclinical models due to fragment design
Forms soldLyophilized vial

What is TB-500?

Preclinical research has investigated TB-500 in models of cardiac repair, dermal wound healing, corneal injury, and musculoskeletal damage, with a focus on cell migration, angiogenesis, and inflammation modulation.

TB-500 is frequently stacked with BPC-157 in research settings (the combination is often marketed as the Wolverine blend). When comparing suppliers, verify that the COA matches the fragment sequence actually being sold, as some vendors substitute full thymosin beta-4 or unrelated peptides.

Mechanism of Action (Research Context)

Studied for actin sequestration regulation, promotion of cell migration and differentiation, angiogenesis support, and reduction of inflammatory markers in animal injury models.

Research Areas

Cardiac tissue repair modelsWound healing researchCorneal injury modelsMuscle and tendon researchAnti-fibrotic research

TB-500 Dosages in Research

5mg10mg

Preclinical research protocols in animal models commonly reference milligram-range weekly dosing split across administrations. Sold almost exclusively as 5mg and 10mg lyophilized vials for laboratory reconstitution. Research use only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C for long-term storage. Reconstituted: 2-8C, use within 30 days. Avoid repeated freeze-thaw.

TB-500 Supplier Price Comparison

SupplierProductPriceScore
Verified Peptides TB-500 ★ 5.6
Verified Peptides TB-500 $37.20 ★ 5.6
Buy Peptides TB-500 Spray $89.99 ★ 2.3

TB-500 FAQ

No. TB-500 is a synthetic fragment based on the active region of Thymosin Beta-4. Some vendors sell the full 43-amino-acid protein instead, so the COA should confirm exactly which molecule is in the vial.
The two peptides are studied through complementary pathways - TB-500 for cell migration and angiogenesis, BPC-157 for growth factor modulation - so researchers often examine them together in tissue repair models.
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