SNAP-8: Research Profile, Dosages & Supplier Prices

Cosmetic / tissue research · Lyophilized powder · Also known as: Acetyl Octapeptide-3, Ac-EEMQRRAD-NH2

SNAP-8 is a cosmetic / tissue research compound with a molecular weight of 1075.2 g/mol and a research half-life of topical/local research use. SNAP-8 (acetyl octapeptide-3) is the second-generation successor to Argireline: the same SNAP-25-mimetic N-terminal motif extended by two amino acids (Ala-Asp) for improved SNARE-complex interference. It targets the same pathway - acetylcholine release at the neuromuscular junction - with cosmetic studies reporting stronger wrinkle-depth reduction than its predecessor.

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

Sequence	Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
Formula	C41H70N16O16S
Mol. weight	1075.2 g/mol
Half-life	Topical/local research use
Forms sold	Lyophilized powder

What is SNAP-8?

Like Argireline it is used in topical anti-expression-line research and as a SNARE-complex tool compound. The two are frequently compared head-to-head in formulation studies, and SNAP-8 is often chosen where maximum non-invasive SNARE modulation is the research goal. It is one of the most counterfeited cosmetic peptides because synthesis of the 8-mer with correct N-acetylation and C-amidation is non-trivial at low cost.

Mechanism of Action (Research Context)

Extended SNAP-25 mimetic: competes for SNARE complex assembly more effectively than the hexapeptide Argireline, reducing vesicle fusion and acetylcholine release at neuromuscular junctions in research models.

Research Areas

SNARE complex biologyExpression-line / wrinkle modelsTopical peptide formulationComparative neurocosmetic peptide studies

SNAP-8 Dosages in Research

100mg1g (cosmetic formulation research)

Cosmetic research formulations typically use 3-10% solutions. Research-context only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C desiccated. In solution or formulation: 2-8C, protected from light; use within weeks.

SNAP-8 Supplier Price Comparison

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SNAP-8 FAQ

SNAP-8 is Argireline extended by two amino acids (Ala-Asp) at the C-terminus. The octapeptide interferes with SNARE complex formation more strongly in comparative studies and is considered the second-generation compound.

Topical expression-line reduction research and SNARE-complex pharmacology, usually benchmarked against Argireline.

98%+ HPLC purity and mass spec identity at 1075.2 Da, with confirmation of N-terminal acetylation and C-terminal amidation - both are required for activity.

Age & Use Verification