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All products discussed on this site are Research Use Only (RUO) compounds intended strictly for laboratory research. Nothing here is medical advice, and these products are not for human or veterinary use.

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Sermorelin: Research Profile, Dosages & Supplier Prices

Growth hormone secretagogue · Lyophilized vial · Also known as: GRF 1-29, GHRH (1-29), sermorelin acetate

Sermorelin is a growth hormone secretagogue compound with a molecular weight of 3357.9 g/mol and a research half-life of approximately 10-20 minutes in published human pharmacokinetic data. Sermorelin is the biologically active 1-29 fragment of growth hormone-releasing hormone (GHRH) and was previously an FDA-approved diagnostic agent (Geref) for growth hormone deficiency before being discontinued for commercial reasons unrelated to safety.

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

SequenceTyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
FormulaC149H246N44O42S
Mol. weight3357.9 g/mol
Half-lifeApproximately 10-20 minutes in published human pharmacokinetic data
Forms soldLyophilized vial

What is Sermorelin?

Because of its pharmaceutical history, sermorelin has unusually deep human pharmacology literature for a research peptide, including pediatric and adult GH axis studies. It remains a compounding-pharmacy staple and a common research peptide.

Sermorelin is a 29-amino-acid linear peptide - a moderately complex synthesis. Verify batch COAs show HPLC purity and mass spec identity, particularly from discount vendors.

Mechanism of Action (Research Context)

GHRH receptor agonist stimulating pulsatile growth hormone release from the pituitary in research models.

Research Areas

Growth hormone axis researchGHRH pharmacologyPituitary function studies

Sermorelin Dosages in Research

2mg5mg10mg

Published clinical research used weight-based microgram dosing in human subjects. Research vials commonly 2-10mg. Laboratory research use only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C. Reconstituted: 2-8C, use within 20-30 days.

Sermorelin Supplier Price Comparison

SupplierProductPriceScore
Certified Pep SERMORELIN 5MG 5mg $55.00 ★ 9.8
Buy Peptides Sermorelin Spray $59.99 ★ 2.3
Certified Pep SERMORELIN 10MG 10mg $95.00 ★ 9.8

Sermorelin FAQ

No. Sermorelin is the unmodified GHRH 1-29 fragment. CJC-1295 (Mod GRF) has four amino acid substitutions for stability, and the DAC version adds an albumin-binding moiety. They are different molecules with different COAs.
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