Retatrutide: Research Profile, Dosages & Supplier Prices
Retatrutide is a triple agonist compound with a molecular weight of 4731.4 g/mol and a research half-life of approximately 6 days in published phase 2 pharmacokinetic data. Retatrutide is a triple receptor agonist peptide - activating GIP, GLP-1, and glucagon receptors - developed by Eli Lilly and currently in phase 3 clinical trials. Published phase 2 data (New England Journal of Medicine, 2023) showed the largest weight reduction recorded in a metabolic drug trial at that time, with the highest dose group averaging over 24% body weight reduction at 48 weeks.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | 39-amino-acid peptide with fatty acid modification (structure published in trial literature) |
| Formula | C221H342N46O68 |
| Mol. weight | 4731.4 g/mol |
| Half-life | Approximately 6 days in published phase 2 pharmacokinetic data |
| Forms sold | Lyophilized vial (research) |
What is Retatrutide?
Because retatrutide is not yet an approved drug, it exists only in the research market, which makes it both high-demand and high-risk for counterfeiting. Research interest focuses on triple-agonist pharmacology and the role of glucagon receptor activation in energy expenditure.
This is currently one of the most counterfeited research peptides. Any vendor selling retatrutide without batch-specific third-party mass spectrometry should be treated as suspect.
Mechanism of Action (Research Context)
Triple agonist at GIP, GLP-1, and glucagon receptors. Glucagon receptor activation is studied for increasing energy expenditure and hepatic fat metabolism in addition to incretin effects.
Research Areas
Retatrutide Dosages in Research
Published phase 2 research titrated once-weekly doses from 1mg up to 12mg in human subjects. Research vials commonly 5mg and 10mg. Laboratory research use only.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Lyophilized: -20C. Reconstituted: 2-8C, use within 30 days.
Retatrutide Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| peptidesarm.com | Retatrutide (LY3437943) CAS#2381089-83-2 raw materials | — | ★ 2.9 |
| Leading Peptide Research Company | Retatrutide 10mg 10mg | — | ★ 2.2 |
| Medical Consumables & Drug Delivery Solutions | 10mg Disposable Injection Pen for Retatrutide 10mg | — | ★ 1.6 |
| Home | Retatrutide 40mg COA 40mg | — | ★ 2.0 |
| Medical Consumables & Drug Delivery Solutions | 10mg Disposable pen injector assembly for Retatrutide 10mg | — | ★ 1.6 |
| Research Peptides UK | Retatrutide — Education Page Only (Triple-Agonist) | — | ★ 2.0 |
| Peptides, Steroid Powders & Biochemical Raw Materials | Retatrutide 10mg/vial Lyophilized Peptide | Research Grade for Metabolic & Obesity Studies 10mg | — | ★ 1.8 |
| Home | Retatrutide 20mg COA 20mg | — | ★ 2.0 |
| Medical Consumables & Drug Delivery Solutions | Retatrutide Injection Pen 10mg Manufacturer | OEM Disposable Auto Injector 10mg | — | ★ 1.6 |
| Home | Retatrutide | — | ★ 2.8 |
| Calibrate IV | Retatrutide (12mg) 12mg | — | ★ 3.7 |
| Advance Peptides Lab | Retatrutide 10mg 10mg | — | ★ 1.6 |
| Advance Peptides Lab | Retatrutide 20mg 20mg | — | ★ 1.6 |
| Buy Peptides: Australian Amino Shop with Global Shipping | Retatrutide | $0.79 | ★ 1.5 |
| AION | Retatrutide – GLP 20Mg 20Mg | $1.00 | ★ 1.7 |
| AION | Retatrutide – GLP 10Mg 10Mg | $1.00 | ★ 1.7 |
| Cartman Gear | RETATRUTIDE | $3.00 | ★ 1.8 |
| Cartman Gear | Lobster Retatrutide 10mg X 10 Vials Australia Domestic 10mg | $6.00 | ★ 1.8 |
| Cartman Gear | Lobster Retatrutide 20mg X 10 Vials Australia Domestic 20mg | $9.00 | ★ 1.8 |
| Cartman Gear | Lobster Retatrutide 30mg X 10 Vial Australia Domestic 30mg | $12.00 | ★ 1.8 |
| Chongshan Medical Beauty – Guangzhou Chongshan Medical Technology Co., Ltd. | Weight Loss Peptide Retatrutide Lyophilized Powder | $12.00 | ★ 1.8 |
| Home | Retatrutide | $13.00 | ★ 1.5 |
| Agonist Solutions | Retatrutide 5 mg 5 mg | $20.00 | ★ 1.6 |
| Research Peptides UK | Retatrutide | $20.95 | ★ 1.6 |
| Bangkok Peptide Center | Retatrutide 10mg 10mg | $35.00 | ★ 1.6 |
| Home | Retatrutide | $35.00 | ★ 1.5 |
| Buy Research Peptides UK | Retatrutide 10MG 10MG | $39.00 | ★ 1.8 |
| Aussie Peptides | Retatrutide | $40.00 | ★ 1.5 |
| Helix Research Co. – Shop Smart, Live Better | Retatrutide | $40.00 | ★ 1.5 |
| Apex Peptides | Retatrutide | $44.00 | ★ 2.3 |
| Age Verification | Retatrutide Single Vial | $47.62 | ★ 2.0 |
| Home | Retatrutide | $49.00 | ★ 1.4 |
| Home | Retatrutide 5mg 5mg | $50.00 | ★ 1.6 |
| High | Retatrutide Canada – Research Peptide | $50.00 | ★ 1.8 |
| BOC Peptide | Retatrutide | $50.00 | ★ 1.5 |
| Agonist Solutions | Retatrutide 20 mg 20 mg | $50.00 | ★ 1.6 |
| Lush·Aminos – Research | RETATRUTIDE | $50.00 | ★ 1.4 |
| Home | Retatrutide | $50.00 | ★ 1.4 |
| Muscles Secrets | Viking Retatrutide 10 mg -Vials 10mg | $50.00 | ★ 2.1 |
| Ascend Peptides | Retatrutide | $59.99 | ★ 1.9 |
| Ancaris Labs | GLP3-Retatrutide | $60.00 | ★ 1.4 |
| Buy Research Peptides Online — 99% Purity, COA | Retatrutide 5mg 5mg | $60.00 | ★ 2.2 |
| Agonist Solutions | Retatrutide 30 mg 30 mg | $60.00 | ★ 1.6 |
| Buy Peptides Canada | Retatrutida de 5, 10, 30 y 60 mg para investigación en Canadá 5mg | $63.99 | ★ 2.3 |
| Buy Peptides Canada | Rétatrutide 5 mg, 10 mg, 30 mg et 60 mg — Peptide de recherche au Canada 5mg | $63.99 | ★ 2.3 |
| Buy Peptides Canada | Retatrutide 5mg, 10mg, 30mg & 60mg — Research Peptide Canada 5mg, 10mg, 30mg & 60mg | $63.99 | ★ 2.3 |
| Home | GLP-3 Retatrutide – 5mg-60mg 5mg-60mg | $64.00 | ★ 1.8 |
| Home | Buy Retatrutide Peptide Online-5mg . 5mg | $65.00 | ★ 2.3 |
| Black Helix Labs | Retatrutide (5mg) **NO LABEL** 5mg | $65.00 | ★ 1.6 |
| Pure Peptides UK | Alpha-R 15mg (Reta) 15mg | $65.00 | ★ 2.7 |