Noopept: Research Profile, Dosages & Supplier Prices
Noopept is a neuropeptide research compound with a molecular weight of 318.4 g/mol and a research half-life of short (~30-60 min parent; active metabolite cycloprolylglycine persists). Noopept (GVS-111) is a synthetic dipeptide-derived nootropic developed in Russia, structurally based on the endogenous cyclic dipeptide cycloprolylglycine. Though often grouped with racetams, it is pharmacologically distinct and active at far lower doses. It is approved as a cognitive medication in Russia and widely sold elsewhere as a research compound.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | Dipeptide-derived: phenylacetyl-Pro-Gly ethyl ester |
| Formula | C17H22N2O4 |
| Mol. weight | 318.4 g/mol |
| Half-life | Short (~30-60 min parent; active metabolite cycloprolylglycine persists) |
| Forms sold | Powder (oral) |
What is Noopept?
Preclinical research shows neuroprotective, anxiolytic and cognition-enhancing effects, with proposed mechanisms including increased BDNF/NGF expression, cholinergic modulation, AMPA-receptor effects and antioxidant activity. Its active metabolite cycloprolylglycine is itself an endogenous peptide with anti-amnesic properties. Noopept has a modest human trial literature from Russia alongside a much larger animal literature.
Mechanism of Action (Research Context)
Prodrug-like behavior: rapidly metabolized to cycloprolylglycine. Increases hippocampal BDNF and NGF expression, modulates cholinergic and glutamatergic (AMPA) transmission, and shows antioxidant and anti-inflammatory effects in neural tissue.
Research Areas
Noopept Dosages in Research
Russian clinical use was 10-30 mg/day orally. Active at milligram doses unlike gram-dose racetams. Research-context only outside approved markets.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Powder: room temperature or 2-8C, desiccated, protected from light. Stable for a peptide-derived compound.
Noopept Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| Buy Research Chemicals USA | Noopept | $0.60 | ★ 2.1 |
| Ladasten – Bromantane Manufactured & Shipped from Poland | Noopept — ≥99.48% Purity Research Reagent | $8.39 | ★ 2.2 |
| Albochemicals LLC – Lab and Science Supplies, High Quality Laboratory Chemicals, APIs and Excipients | N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept, CAS 157115-85-0) ≥99%, 10 Grams 10 grams | $18.48 | ★ 3.2 |
| Home | Noopept | $20.00 | ★ 2.9 |
| Albochemicals LLC – Lab and Science Supplies, High Quality Laboratory Chemicals, APIs and Excipients | N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept, CAS 157115-85-0) ≥99%, 25 grams 25g | $25.50 | ★ 3.2 |
| Official Amino Asylum Website | Noopept | $34.99 | ★ 2.2 |
| Suspended Domain | Noopept | $34.99 | ★ 2.3 |
| Amino Asylum Official Site | Noopept | Amino Asylum Research Compound | $34.99 | ★ 2.2 |
| Albochemicals LLC – Lab and Science Supplies, High Quality Laboratory Chemicals, APIs and Excipients | N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept, CAS 157115-85-0) ≥99%, 50 Grams 50g | $49.90 | ★ 3.2 |