MOTS-c: Research Profile, Dosages & Supplier Prices
MOTS-c is a mitochondrial research compound with a molecular weight of 2174.6 g/mol and a research half-life of short plasma half-life in preclinical models; tissue-level effects persist longer. MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene - part of a recently discovered class of signaling peptides made by mitochondria rather than nuclear DNA. It was first described in 2015 and has become one of the fastest-growing research peptides.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Formula | C101H152N28O22S2 |
| Mol. weight | 2174.6 g/mol |
| Half-life | Short plasma half-life in preclinical models; tissue-level effects persist longer |
| Forms sold | Lyophilized vial |
What is MOTS-c?
Published preclinical research has investigated MOTS-c in metabolic regulation (AMPK pathway activation), exercise capacity models, insulin sensitivity research, and age-related metabolic decline. Rodent studies published in Cell Metabolism and Nature Communications drew significant attention to its exercise-mimetic properties.
MOTS-c synthesis is moderately complex. When comparing suppliers, confirm mass spec identity (2174.6 g/mol) and check whether the vendor publishes endotoxin testing, which matters for metabolic research models.
Mechanism of Action (Research Context)
Studied for AMPK activation, folate-purine pathway modulation, and nuclear translocation under metabolic stress in cell and animal models.
Research Areas
MOTS-c Dosages in Research
Preclinical rodent research commonly references the 5-15 mg/kg range. Research vials typically 10mg. Laboratory research use only.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Lyophilized: -20C. Reconstituted: 2-8C, use within 30 days.
MOTS-c Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| Verified Peptides | MOTS C | $25.80 | ★ 5.6 |
| Buy Peptides | MOTS-C Spray | $49.99 | ★ 2.3 |
| Certified Pep | MOTS C 10MG 10mg | $58.00 | ★ 9.8 |
| Buy Peptides | MOTS-C (1 Vial) | $69.99 | ★ 2.3 |
| Research Peptides For Sale Online | MOTS-C | $76.99 | ★ 2.1 |
| Certified Pep | MOTS C 20MG 20mg | $90.00 | ★ 9.8 |
| Certified Pep | MOTS C 40MG 40mg | $160.00 | ★ 9.8 |