MOTS-c: Research Profile, Dosages & Supplier Prices
MOTS-c is a mitochondrial research compound with a molecular weight of 2174.6 g/mol and a research half-life of short plasma half-life in preclinical models; tissue-level effects persist longer. MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene - part of a recently discovered class of signaling peptides made by mitochondria rather than nuclear DNA. It was first described in 2015 and has become one of the fastest-growing research peptides.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Formula | C101H152N28O22S2 |
| Mol. weight | 2174.6 g/mol |
| Half-life | Short plasma half-life in preclinical models; tissue-level effects persist longer |
| Forms sold | Lyophilized vial |
What is MOTS-c?
Published preclinical research has investigated MOTS-c in metabolic regulation (AMPK pathway activation), exercise capacity models, insulin sensitivity research, and age-related metabolic decline. Rodent studies published in Cell Metabolism and Nature Communications drew significant attention to its exercise-mimetic properties.
MOTS-c synthesis is moderately complex. When comparing suppliers, confirm mass spec identity (2174.6 g/mol) and check whether the vendor publishes endotoxin testing, which matters for metabolic research models.
Mechanism of Action (Research Context)
Studied for AMPK activation, folate-purine pathway modulation, and nuclear translocation under metabolic stress in cell and animal models.
Research Areas
MOTS-c Dosages in Research
Preclinical rodent research commonly references the 5-15 mg/kg range. Research vials typically 10mg. Laboratory research use only.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Lyophilized: -20C. Reconstituted: 2-8C, use within 30 days.
MOTS-c Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| Home | MOTs-c 10mg COA 10mg | — | ★ 2.0 |
| Home | MOTS-C (Mitochondrial Open Reading Frame) | — | ★ 2.8 |
| Peptide Manufacturer & Supplier | MOTS-C 10MG 10mg | — | ★ 1.8 |
| Evolve Anti | MOTS-C | — | ★ 2.5 |
| Advance Peptides Lab | MOTS-C (10mg) 10mg | — | ★ 1.6 |
| Leading Peptide Research Company | MOTS-c 10mg 10mg | — | ★ 2.2 |
| Complete Wellness & Aesthetics: Medical Weight Loss, Med Spa | MOTS-C | — | ★ 1.7 |
| Classic Shop | MOTS-c 10mg Prefilled Injection Pen 10mg | $0.55 | ★ 1.7 |
| AION | Mots-C 10Mg 10Mg | $1.00 | ★ 1.7 |
| Cartman Gear | MOTS-C | $3.40 | ★ 1.8 |
| Chongshan Medical Beauty – Guangzhou Chongshan Medical Technology Co., Ltd. | MOTS-c Lyophilized Powder – Cellular Energy & Mitochondrial Function | $9.50 | ★ 1.8 |
| UK Research Peptide Supplier | MOTS-C 10mg 10mg | $14.99 | ★ 1.7 |
| Aussie Peptides | Mots-c | $15.00 | ★ 1.5 |
| Bangkok Peptide Center | MOTS-C 10mg 10mg | $15.00 | ★ 1.6 |
| Glow Bougie | MOTS-C 10mg Vial 10mg | $15.00 | ★ 2.5 |
| Research Peptides UK | MOTS-c 10mg 10mg | $17.95 | ★ 1.6 |
| Research Peptides & Compounds for Labs | MOTS-c — Single Vial | $18.99 | ★ 1.9 |
| Cielo – Lab | MOTS-C | $20.00 | ★ 1.5 |
| Jett Labs Research – Research Grade Compounds | MOTS-C (10mg) 10mg | $21.00 | ★ 2.0 |
| Research Peptides & Laboratory Supplies UK | MOTS-C 10mg 10mg | $21.00 | ★ 1.9 |
| Pure Peptides UK | MOTS-c 10mg 10mg | $22.00 | ★ 2.7 |
| HUK Aesthetics | MOTS-C 10mg 10mg | $22.00 | ★ 3.2 |
| Buy Research Peptides UK | MOTS-C 10MG 10MG | $23.00 | ★ 1.8 |
| Research | MOTS-c | $23.50 | ★ 1.6 |
| Buy Research Peptides UK | MOTS-c 10mg 10mg | $24.99 | ★ 1.6 |
| Natty Lab Co · Research Materials, Done Right | MOTS-c 10MG 10mg | $25.00 | ★ 1.9 |
| Home | MOTS-c – 20mg Batch #102 Research Peptide 20mg | $25.00 | ★ 1.5 |
| Anglo Peptides | MOTS-c – 10mg Batch #107 Research Peptide 10mg | $25.00 | ★ 1.6 |
| Home | MOTS-c | $25.00 | ★ 1.5 |
| Home | MOTS-c – 10mg Batch #107 Research Peptide 10mg | $25.00 | ★ 1.5 |
| Home | MOTS-C 10 mg 10mg | $25.00 | ★ 2.7 |
| Home Page | MOTS-C 10mg 10mg | $26.00 | ★ 1.4 |
| AURA Peptides UK | MOTS-C 10mg – Pre Order 10% Off 10mg | $26.99 | ★ 1.6 |
| Astra Labs | MOTS-C 10mg 10mg | $29.99 | ★ 1.6 |
| One moment, please... | MOTS-c | $29.99 | ★ 1.6 |
| Research Peptides UK | Adonis MOTS-C – Research Peptide – (RUO) | $29.99 | ★ 2.0 |
| K2 Compounds – Cutting Edge Research Products | MOTS-C – 10mg 10mg | $30.00 | ★ 2.3 |
| Agonist Solutions | Mots C 10 mg 10 mg | $30.00 | ★ 1.6 |
| Age Verification | MOTS C 10MG 10mg | $30.00 | ★ 1.7 |
| Peptides UK Premium Research Peptides Apollo Labs | MOTS-C | $30.00 | ★ 2.0 |
| AminoX Peptides – For Research Purposes | MOTS-C-10MG/10kits 200$ 10mg | $30.00 | ★ 1.8 |
| Buy Research Peptides UK | MOTS-C – 10mg | Research-Grade Peptide 10mg | $30.00 | ★ 1.6 |
| Accurate Peptide Supply – Same Sequence. Same Result. Every Time. | MOTS-c 10mg 10mg | $30.38 | ★ 1.4 |
| AIO Peptides: Buy High | MOTS-C 10mg 10mg | $34.00 | ★ 2.0 |
| BAYOUPEP USA | MOTS-c | $34.59 | ★ 1.8 |
| Alpha BioPharma | MOTS-C | $34.95 | ★ 2.1 |
| Alera Research | Mots-C – 10mg 10mg | $34.99 | ★ 1.7 |
| Altus Lab | MOTS-C | $35.00 | ★ 1.6 |
| Home | MOTS-C 10mg 10mg | $35.00 | ★ 2.0 |
| Alpha Omega Peptides | MOTS-C 10MG 10MG | $35.00 | ★ 2.3 |