LL-37: Research Profile, Dosages & Supplier Prices
LL-37 is a immune research compound with a molecular weight of 4493.3 g/mol and a research half-life of short (rapid proteolytic turnover). LL-37 is the only human member of the cathelicidin family of antimicrobial peptides - a 37-amino-acid alpha-helical peptide cleaved from the hCAP-18 precursor protein. It is produced by neutrophils, epithelial cells and keratinocytes and serves as a first-line innate immune effector with direct broad-spectrum antimicrobial activity against bacteria, fungi and enveloped viruses.
Research Use Only (RUO). Not for human or veterinary use. Not medical advice.
| Sequence | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
| Formula | C205H340N60O53 |
| Mol. weight | 4493.3 g/mol |
| Half-life | Short (rapid proteolytic turnover) |
| Forms sold | Lyophilized powder |
What is LL-37?
Beyond direct pathogen killing, LL-37 is heavily studied as an immune modulator: it chemoattracts immune cells, neutralizes bacterial endotoxin (LPS), modulates TLR signaling, and influences wound healing and angiogenesis. Research spans infection models, biofilm disruption, inflammatory bowel disease, psoriasis (where LL-37 is implicated as an autoantigen), and even cancer biology. Its dual pro- and anti-inflammatory behavior makes it one of the more context-dependent peptides in the research catalog.
Mechanism of Action (Research Context)
Amphipathic alpha-helix inserts into and disrupts microbial membranes (carpet/toroidal-pore models). Binds and neutralizes LPS. Immunomodulatory actions via FPRL-1/FPR2, P2X7 and EGFR transactivation; chemotactic for neutrophils, monocytes and T cells.
Research Areas
LL-37 Dosages in Research
Cell-culture antimicrobial assays typically use low micromolar concentrations; animal infection models use microgram-per-kilogram dosing. Research-context only.
Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.
Storage & Handling
Lyophilized: -20C desiccated. Reconstituted: 2-8C, use within 1-2 weeks. LL-37 aggregates readily in solution - prepare fresh dilutions and avoid repeated freeze-thaw.
LL-37 Supplier Price Comparison
| Supplier | Product | Price | Score |
|---|---|---|---|
| Alpha and Omega Peptides | LL-37 | — | ★ 1.9 |
| Wholesale high | LL-37 Peptide raw material wholesale | $16.00 | ★ 2.6 |
| Research Peptides UK | LL-37 5mg 5mg | $19.95 | ★ 1.6 |
| MyPurePeptide | LL-37 5mg 5mg | $20.00 | ★ 1.5 |
| Accelerate Labs – High Purity Research Peptides & Amino Derivatives | LL-37 10MG 10MG | $32.99 | ★ 2.3 |
| AIO Peptides: Buy High | LL-37 5mg 5mg | $36.00 | ★ 2.0 |
| Just Compounds | LL-37 | $39.99 | ★ 1.7 |
| Alpha Omega Peptides | LL-37 | $40.00 | ★ 2.3 |
| Alpha Omega Peptides: Buy High | LL-37 | $45.00 | ★ 2.3 |
| alpha omega peptides | LL-37 | $45.00 | ★ 2.3 |
| Research Peptides & Laboratory Materials | LL-37 | $45.00 | ★ 2.6 |
| Alpha omega peptide | LL-37 | $45.00 | ★ 2.3 |
| Buy Alpha Omega Peptides | LL-37 | $45.00 | ★ 2.3 |
| Buy Research Peptides Online | LL-37 5MG 5MG | $45.00 | ★ 2.0 |
| Home | LL-37 5MG 5MG | $45.00 | ★ 1.8 |
| Home | LL-37 5mg 5mg | $49.00 | ★ 1.9 |
| Apex Body Labs | LL-37 (5mg) 5mg | $49.50 | ★ 1.8 |
| Home | LL-37 | $50.00 | ★ 1.9 |
| Research Materials | LL-37 | $50.00 | ★ 1.7 |
| AminoX Peptides – For Research Purposes | LL37 5 Mg 5mg | $50.00 | ★ 1.8 |
| 24Peptides | LL-37 5mg 5mg | $54.00 | ★ 2.2 |
| American Peptide Innovations | LL37 (5mg) 5mg | $55.00 | ★ 1.9 |
| Nootropic Source | LL-37 Acetate | $64.95 | ★ 3.2 |
| Buy Research Peptides, Third | LL-37 Peptide (5MG) 5MG | $65.00 | ★ 5.7 |
| Buy the best Anabolic Steroids, SARMs & Peptides | LL-37 – 10mg 10mg | $69.99 | ★ 3.2 |
| Aesentra EU | LL-37 5mg Research Peptide 5mg | $69.99 | ★ 1.8 |
| Advanced Peptide Research | LL-37 | $69.99 | ★ 1.9 |
| Apollo Peptides – Research | LL-37 | $70.00 | ★ 1.8 |
| Australian Peptides Store | LL37 Peptide 5mg × 10 vials 5mg | $70.00 | ★ 2.4 |
| One moment, please... | LL-37 (5mg) 5mg | $72.99 | ★ 2.0 |
| Aura Peptides USA | LL-37 5 mg 5 mg | $75.00 | ★ 2.0 |
| Research Peptides in the USA | LL-37 (Cathelicidin) Peptide | $75.00 | ★ 2.1 |
| Apex DNA Peptides | LL37 (5mg) 5mg | $75.00 | ★ 1.9 |
| Azoth Peptides | LL-37 | $75.00 | ★ 1.7 |
| Home | LL-37 5 mg 5 mg | $75.00 | ★ 2.0 |
| Atomik Labs Peptides: Buy High | LL-37 -5mg 5mg | $77.00 | ★ 2.3 |
| Ascension Peptides – Your premiere source for research peptides | LL-37 (10MG) 10mg | $78.00 | ★ 2.3 |
| Apex Peptides | LL-37 5mg 5mg | $79.00 | ★ 2.3 |
| Research Peptides for Sale – US | LL-37 (1 Vial) | $79.99 | ★ 2.2 |
| Peptides for Scientific Discovery | LL-37 | $79.99 | ★ 1.8 |
| Amino USA: Premium & Third | LL-37 5mg 5mg | $80.00 | ★ 2.2 |
| Home | LL-37 10mg 10mg | $80.00 | ★ 2.5 |
| Alpha Amino Labs | LL37 (5mg) 5mg | $80.00 | ★ 1.9 |
| Home | LL-37 5mg 5mg | $80.00 | ★ 2.9 |
| Research Peptides USA | LL-37 5mg 5mg | $80.00 | ★ 2.7 |
| Buy Peptides for Laboratory Research | LL-37 5mg (CAP-18) 5mg | $84.99 | ★ 2.8 |
| Apextide Biolaps | LL-37 5mg 5mg | $85.00 | ★ 1.8 |
| Elitecare Pharmacy – Advanced Peptide Solutions. Precision You Can Trust. | LL37 | $85.00 | ★ 1.8 |
| 808 Peptides LLC | LL37 (5mg) 5mg | $88.00 | ★ 1.9 |
| Ascension Peptides | LL-37 10mg Research Peptide 10mg | $89.00 | ★ 1.7 |