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All products discussed on this site are Research Use Only (RUO) compounds intended strictly for laboratory research. Nothing here is medical advice, and these products are not for human or veterinary use.

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CJC-1295: Research Profile, Dosages & Supplier Prices

Growth hormone secretagogue · Lyophilized vial · Also known as: Modified GRF 1-29, Mod GRF, CJC-1295 No DAC, CJC-1295 DAC

CJC-1295 is a growth hormone secretagogue compound with a molecular weight of 3367.9 g/mol (Mod GRF 1-29) and a research half-life of mod grf (no dac): ~30 minutes. cjc-1295 with dac: 6-8 days in published research. CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH 1-29) with four amino acid substitutions that protect it from enzymatic degradation. It exists in two distinct forms that researchers must distinguish: CJC-1295 with DAC (Drug Affinity Complex), which binds albumin and extends half-life to roughly a week, and CJC-1295 without DAC - more accurately called Modified GRF 1-29 - which has a short ~30 minute half-life and produces more physiological pulsatile GH release in research models.

Research Use Only (RUO). Not for human or veterinary use. Not medical advice.

SequenceTyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 (Mod GRF 1-29 core)
FormulaC152H252N44O42 (Mod GRF 1-29)
Mol. weight3367.9 g/mol (Mod GRF 1-29)
Half-lifeMod GRF (no DAC): ~30 minutes. CJC-1295 with DAC: 6-8 days in published research
Forms soldLyophilized vial

What is CJC-1295?

Published clinical research on CJC-1295 with DAC demonstrated dose-dependent increases in GH and IGF-1 levels in human subjects, making it one of the few research peptides with formal human pharmacokinetic data.

Supplier red flag: many vendors label vials as CJC-1295 without specifying DAC or no-DAC. These are materially different molecules with different molecular weights - always confirm which version the COA covers.

Mechanism of Action (Research Context)

GHRH receptor agonist at the pituitary, stimulating growth hormone synthesis and release. The DAC version covalently binds serum albumin, dramatically extending circulation time.

Research Areas

Growth hormone axis researchIGF-1 modulation studiesGHRH receptor pharmacologyPulsatile vs sustained GH release comparison

CJC-1295 Dosages in Research

2mg5mg

Published human research on the DAC version used weekly subcutaneous administration in the 30-60 mcg/kg range. Mod GRF 1-29 (no DAC) animal research typically references ~100 mcg per administration. Laboratory research use only.

Dosage information is a summary of published laboratory research and is provided for informational purposes only. These compounds are not for human use.

Storage & Handling

Lyophilized: -20C long-term. Reconstituted: 2-8C, use within 20-30 days. The DAC version is somewhat more fragile once reconstituted.

CJC-1295 Supplier Price Comparison

SupplierProductPriceScore
Buy Peptides CJC-1295 With DAC (1 Vial) $49.99 ★ 2.3

CJC-1295 FAQ

CJC-1295 with DAC binds albumin and lasts about a week per administration in research models. CJC-1295 No DAC (Modified GRF 1-29) has a ~30 minute half-life and produces short, pulsatile GH release. They have different molecular weights and should have different COAs.
They act on complementary receptors - GHRH receptor and ghrelin receptor - so research models combine them to study synergistic GH release.
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